| ORAL THERAPY FOR UTIs IN ADULTS | |||||
|---|---|---|---|---|---|
| Generic | Brand and Manufacturer | Formulation | Strength | Dose | Duration |
| CEPHALOSPORINS | |||||
| Cefadroxil | (various) | caps | 500mg | 1–2g once daily or in 2 divided doses.
Complicated: 2g/day in 2 divided doses |
10 days |
| tabs | 1g | ||||
| susp | 250mg/5mL, 500mg/5mL | ||||
| Cephalexin | Keflex | caps | 250mg, 500mg, 750mg | 500mg every 12 hours; max 4g/day | 7–14 days |
| NITROFURANTOINS | |||||
| Nitrofurantoin | Furadantin | susp | 25mg/5mL | 50–100mg 4 times daily. Suppressive therapy: 50–100mg once daily at bedtime may suffice |
7 days |
| Macrobid | caps | 100mg | 100mg every 12 hours | 7 days | |
| Macrodantin | caps | 25mg, 50mg, 100mg | 50–100mg 4 times daily. Long-term use: 50–100mg once daily at bedtime |
7 days | |
| PENICILLINS | |||||
| Amoxicillin | Amoxil | caps | 250mg, 500mg | 500mg every 12 hours or 250mg every 8 hours | |
| tabs | 500mg, 875mg | ||||
| chewable | 200mg, 400mg | ||||
| drops | 50mg/mL | ||||
| susp | 125mg/5mL, 200mg/5mL, 250mg/5mL, 400mg/5mL | ||||
| Amoxicillin + Clavulanic acid
(clavulanic acid component in |
Augmentin | tabs | 250mg (125mg), 500mg (125mg), 875mg (125mg) | 250mg every 12 hours or 250mg every 8 hours | |
| susp | 125mg (31.25mg)/5mL, 200mg (28.5mg)/5mL, 250mg (62.5mg)/5mL, 400mg (57mg)/5mL |
||||
| chewable | 25mg (31.25mg), 200mg (28.5mg), 250mg (62.5mg), 400mg (57mg) | ||||
| QUINOLONES | |||||
| Ciprofloxacin | Cipro | tabs | 250mg, 500mg, 750mg | Acute uncomplicated cystitis due to E. coli, S. saprophyticus in females: 250mg every 12 hours. |
3 days |
| susp | 250mg/5mL, 500mg/5mL | Other UTIs: 250–500mg every 12 hours | 7–14 days | ||
| Ciprofloxacin ext-rel | Cipro XR | tabs | 500mg, 1g | Uncomplicated UTI: 500mg once daily | 3 days |
| Complicated UTI, acute uncomplicated pyelonephritis: 1000mg once daily |
7–14 days | ||||
| ProQuin XR | tabs | 500mg | Acute uncomplicated UTIs due to E. coli, K. pneumoniae: 500mg once daily |
3 days | |
| Levofloxacin | Levaquin | tabs | 250mg, 500mg, 750mg | 250mg once daily for 3 days | 3 days |
| Complicated: 250mg once daily | 10 days | ||||
| Complicated: 750mg once daily | 5 days | ||||
| Norfloxacin | Noroxin | tabs | 400mg | 400mg every 12 hours for 3 days | 3 days |
| Complicated: 400mg every 12 hours | 10–21 days | ||||
| Ofloxacin | Floxin | tabs | 200mg, 300mg, 400mg | 200mg every 12 hours | 7 days |
| Complicated: 200mg every 12 hours | 10 days | ||||
| SULFONAMIDES | |||||
| Sulfamethoxazole + trimethoprim | Bactrim DS | tabs | 800mg (SMX) + 160mg (TMP) | 1 DS tablet or 2 regular tablets every 12 hours | 10–14 days |
| Septra DS | tabs susp |
800mg (SMX) + 160mg (TMP) 200mg (SMX) + 40mg (TMP)/5mL |
1 DS tablet or 2 regular tablets every 12 hours | 10–14 days | |
| OTHER CLASSES | |||||
| Fosfomycin | Monurol | granules for solution | 3g | Mix contents of 1 sachet (3g) with 3oz to 4oz of water (do not use hot water); drink immediately; max 1 dose/episode |
1 dose |
| Trimethoprim | Primsol | soln | 50mg/5mL | 100mg twice daily, or 200mg once daily | 10 days |
|
(Rev. 11/2011) |
|||||
Oral Therapy for Urinary Tract Infections in Adults
December 15, 2011 By
