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D-aspartic acid is a dietary supplement ingredient based on an amino acid that is found naturally in the body. D-aspartic acid is formed when the enzyme aspartate racemase changes L-aspartic acid into D-aspartic acid in the testes and other glands. It rapidly increases the production of testosterone by increasing the production of signal molecules that regulate the secretion of luteinizing hormone and testosterone.
A study conducted in Italy and published in the journal Reproductive Biology and Endocrinology involved 43 men ages 27 to 37 years: 23 were given 3.12 grams of D-aspartic acid daily and 20 took placebo. Twenty of the 23 men who took D-aspartic acid averaged a 42 percent increase in testosterone levels after 12 days of treatment, and 20 of 23 also showed a significant increase in luteinizing hormone levels. Similar results were seen in rats that were administered D-aspartic acid.
Although the amount of D-aspartic acid found to be effective in this one study was about 3 grams daily, men should consult their healthcare provider before taking D-aspartic acid.
Reference
Topo E et al. The role of molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reprod Biol Endocrin 2009; 7;120
