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Riboflavin, otherwise known as vitamin B2, plays a key role in the production of energy in the body. Other functions include working with vitamin B6 and folate to convert them into active forms, participation in the production of red blood cells, and acting as an antioxidant.
A Swedish study published in May 2009 evaluated more than 1,500 men and found that among eight B vitamins and metabolites, elevated plasma concentrations of riboflavin and choline were linked with an increased risk of prostate cancer. (Johansson 2009) This finding suggests that although riboflavin is an essential nutrient, large doses should be avoided.
The RDA is 1.3 mg for adult males, and since the vitamin is found in dairy, meat, green vegetables, eggs, and enriched cereals and grains, a deficiency is rarely a problem. People who abuse alcohol are at increased risk for deficiency because of decreased intake, decreased absorption, and an impaired ability to utilize the vitamin. Men who are very physically active may have a slightly increased need for riboflavin.
Reference
Johansson M et al. One-carbon metabolism and prostate cancer risk: prospective investigation of seven circulating B vitamins and metabolites. Cancer Epidemiol Biomarkers Prev 2009; 18(5):1538-43.
